Dr. Maaike Van Der Graaff


Since July 2019 I work as a neurologist at Acibadem. Having completed my medical education, I chose to specialize in rehabilitation medicine. In preparation I worked in the neurology department of the St Lucas Hospital (Amsterdam). However, at some point I realized that neurology suited me more than rehabilitation medicine. This led to a change of plan and the decision to specialize in neurology. Upon completion of my specialization I took a fellowship in neuromuscular disease in the AMC (Amsterdam) and subsequently ran a multidisciplinary outpatient clinic for ALS patients for several years, together with the rehabilitation physician. During that time I also worked on my thesis. Caring for ALS patients made a profound impression on me both professionally and personally. After several years I chose to work in a smaller city hospital, where I worked as a general neurologist for ten years. Now I work at Acibadem and I appreciate the work environment, the hospitality for patients and the ease with which care can be organized. For my patients I am a  conscientious neurologist and a good listener.

Specialization / areas of interest

Neuromuscular disease/ALS


Dutch, English, Spanish, French

Work experience

2009 – 2019 Neurologist, BovenIJ ziekenhuis, Amsterdam

2002 – 2008 Neuroloist, AMC/ALS-centrum Amsterdam, in combination with PhD thesis on ALS


2001 – 2002 Fellow neuromuscular diseases, AMC Amsterdam

1996 – 2001 Neurology specialization, St. Lucas Andreas ziekenhuis, Amsterdam

1994 – 1996  Neurology Internship, St. Lucas Andreas ziekenhuis, Amsterdam

1993 – 1994 Specialization in rehabilitation, Jan van Breemen instituut, Amsterdam

1992 – 1993 Neurology Intrernship, St. Lucas ziekenhuis, Amsterdam

1984 – 1992 Medicine, Vrije Universiteit, Amsterdam

1983 – 1984 Human movement sciences, Vrije Universiteit Amsterdam


Upper motor and extra motor involvement in motor neuron disease (2012 UvA, promotor Prof Dr M de Visser)


Second IVIg course in Guillain-Barré syndrome patients with poor prognosis (SID-GBS trial): Protocol for a double-blind randomized,   placebo-controlled clinical trial. Walgaard C, Jacobs BC, Lingsma HF, Steyerberg EW, Cornblath DR, van Doorn PA; Dutch   GBS Study Group.  J Peripher Nerv Syst. 2018 Aug 27.

Upper and extra-motoneuron involvement in early motoneuron disease: a diffusion tensor imaging study. Van der Graaff MM, Sage CA, Caan MW, Akkerman EM, Lavini C, Majoie CB,  Nederveen AJ, Zwinderman AH, Vos F, Brugman F, van den Berg LH, de Rijk MC,   van Doorn PA, Van Hecke W, Peeters RR, Robberecht W, Sunaert S, de Visser M.  Brain. 2011 Apr;134(Pt 4):1211-28. 

Nonrigid point set matching of white matter tracts for diffusion tensor  image analysis. Caan MW, van Vliet LJ, Majoie CB, van der Graaff MM, Grimbergen CA, Vos FM.   IEEE Trans Biomed Eng. 2011 Sep;58(9):2431-40.

MR spectroscopy findings in early stages of motor neuron disease. Van der Graaff MM, Lavini C, Akkerman EM, Majoie ChB, Nederveen AJ, Zwinderman AH, Brugman F, van den Berg LH, de Jong JM, de Visser M.  AJNR Am J Neuroradiol. 2010 Nov;31(10):1799-806.

Vocal cord dysfunction in amyotrophic lateral sclerosis: four cases and a review the literature. Van der Graaff MM, Grolman W, Westermann EJ, Boogaardt HC, Koelman H, van   der Kooi AJ, Tijssen MA, de Visser M.   Arch Neurol. 2009 Nov;66(11):1329-33.

Upper motor neuron and extra-motor neuron involvement in amyotrophic lateral sclerosis: a clinical and brain imaging review. Van der Graaff MM, de Jong JM, Baas F, de Visser M.   Neuromuscul Disord. 2009 Jan;19(1):53-8.

Multidisciplinary ALS care improves quality of life in patients with  ALS. Van den Berg JP, Kalmijn S, Lindeman E, Veldink JH, de Visser M, Van der Graaff MM, Wokke JH, Van den Berg LH.   Neurology. 2005 Oct 25;65(8):1264-7.

Mutations in the slow skeletal muscle fiber myosin heavy chain gene   (MYH7) cause  Laing early-onset distal myopathy (MPD1). Meredith C, Herrmann R, Parry C, Liyanage K, Dye DE, Durling HJ, Duff RM, Beckman K, de Visser M, van der Graaff MM, Hedera P, Fink JK, Petty EM,   Lamont P, Fabian V, Bridges L, Voit T, Mastaglia FL, Laing NG. Am J Hum Genet. 2004 Oct;75(4):703-8.

Unilateral thalamic infarction and vertical gaze palsy: cause or coincidence? Van der Graaff MM, Vanneste JA, Davies GA.  J Neuroophthalmol. 2000 Jun;20(2):127-9.

Status epilepticus due to a ruptured dermoid cyst. Van der Graaff MM, Davies G.   J Neurol Neurosurg Psychiatry 1997;62(3):222